| KEYWEST | Home to a SOUTHERNMOST POINT buoy |
| HORN | A southernmost cape |
| LAKEERIE | Body of water home to Middle Island, the southernmost point of land in Canada |
| PELEE | Point __: southernmost point of mainland Canada |
| LIZARD | - Point; the southernmost point of Britain's mainland (6) |
| TARIFA | Point ___ (southernmost point in continental Europe) |
| PORTLAND | Peninsula joined to the mainland of Dorset by Chesil Beach which marks the Jurassic Coast's southernmost point (8) |
| BILL | Portland ___, narrow promontory on the southernmost point of Dorset; location of a lighthouse (4) |
| CAPEOF | Name said to have been given by Bartolomeu Dias to one of Africa's southernmost points (4,2,6) |
| STORMS | Name said to have been given by Bartolomeu Dias to one of Africa's southernmost points (4,2,6) |
| AGULHAS | Cape ___, southernmost point of the African continent (7) |
| PROMONTORY | Southernmost point of mainland Australia, Wilson's ... |
| AFRICA | Cape Agulhas is its southernmost point (6) |
| CAPEHORN | Southernmost point of Chile (4,4) |
| LAE | Ka ___ (southernmost point of Hawaii) |
| FAREWELL | Cape at the southernmost point of Greenland (8) |
| INDIA | Asian country whose southernmost point is Cape Comorin (5) |
| SOUTHPOLE | Southernmost point on Earth (5,4) |
| PORTLANDBILL | Narrow promontory, the southernmost point of Dorset (8,4) |
| WILSONSPROMONTORY | The southernmost point of the Australian mainland (7,10) |