| JOHNHANCOCK | His signature led all the rest |
| DECLARED | Announced that he raced and led all the way (8) |
| LORDFURY | Sydney stayer led all the way to win 1961 Melbourne Cup (4, 4) |
| AKELA | '[T]he great gray Lone Wolf, who led all the Pack by strength and cunning' in Rudyard Kipling's Jungle Book stories (5) |
| WALK | Grand National winner, ESB, led all the way - as they aptly say. (4,2,4) |
| OFLIFE | Grand National winner, ESB, led all the way - as they aptly say. (4,2,4) |
| NDEBELE | African people having been led all over the place |
| MUDDLE | Confusion when wet earth led all over the place! (6) |
| REMBRANDT | Forename of the Dutch painter who used his signature chiaroscuro technique to create The Night Watch (9) |
| SOUL | The ___ Album (Otis Redding record with his signature genre in the title) |
| SPILLANE | "I, the Jury" introduced his signature detective |
| JONLOVITZ | His signature phrase on "SNL" was "That's the ticket!" |
| DAVISJR | Entertainer famous for his signature song The Candy Man, Sammy ___ |
| ADAM | Skater who dubbed his signature move the "Rippon Lutz" |
| NEEDLE | Point, point, point, point then led all over the place (6) |
| SPINDLE | Turning point in short car journey led all over the place |
| HARLEQUIN | The slapstick-smacking lazzi-playing "zanni", known for his signature mask and variegated diamond-patterned costume (9) |
| LESTERHOLT | NBC journalist who said goodbye to his signature program on Friday after 10 years in the anchor's chair |
| ROREM | His signature symphony's title tells what symphonies do |
| DONADAMS | This puzzle's title was one of his signature lines |