| ANETO | Highest of the Pyrenees, Pico de ___ |
| NETHOU | Pic de ___, highest of the Pyrenees |
| PICO | __ de Aneto (highest of the Pyrenees) |
| PERPIGNAN | French town located at the foot of the Pyrenees near the border with Spain, in the 13th century it was the continental capital of the then Kingdom of Mallorca (9) |
| TEIDE | Pico de ___ (12,000-foot volcano on the Canary Islands) |
| GALLO | Pico de ___ (condiment) |
| PAU | Commune on the northern edge of the Pyrenees, capital of the Pyrenees-Atlantiques departement of France |
| HUESCA | City in Spain at the foot of the Pyrenees which was the residence of the kings of Aragon until 1118 (6) |
| DUKE | Derived from the Latin word "dux" (leader), the highest of the five ranks of the peerage (4) |
| SERAPH | An angel of the highest of the nine orders (6) |
| ANDORRA | Non-EU principality in the high mountains of the Pyrenees between France and Spain; one of the small |
| LOURDES | Town at the foot of the Pyrenees; or, the first name of Madonna's eldest daughter (7) |
| LANGUEDOC | Historical region of France between the foothills of the Pyrenees and the river Rhone (9) |
| PYRENEES | Mountain range along the FrancoSpanish border with the highest peak Pico de Aneto; home of the griffon vulture (8) |
| RORAIMA | Described as an "island in the clouds", highest of the Pacaraima Mountains which inspired Arthur Conan Doyle's The Lost World (7) |
| TENOR | The highest of the ordinary adult singing voice |
| ABOVEALL | The highest of the high, in particular (5,3) |
| BLOTTO | What the highest of the high are (6) |
| EAU | Agua, on the other side of the Pyrenees |
| PAYSBASQUE | French region at the western end of the Pyrenees |