| DYSPEPSIA | Heartburn Pepys said should be treated (9) |
| EYELINERS | Decorative features I said should be put on ships (9) |
| STRAW | What Cromwell said should be painted back is what's insubstantial (5) |
| ANHYDROUS | Your hands should be treated without water (9) |
| HANGOVERS | Weeping boer-bean Schotia brachypetala: A decoction (boiled down syrup) of the bark can be taken to treat heartburn and those painful party memories when you wake up. (9) |
| SWEETFANNYADAMS | Nothing mandates way Fens should be treated (5,5,5) |
| ENHANCE | Hen with acne should be treated to make better (7) |
| ASE | How peers should be treated |
| ENDORSE | Recommend red nose should be treated |
| VIOLATE | Act against something that should be treated with respect (7) |
| RESPECT | A spectre should be treated with it when put out (7) |
| HUSTLER | Swindler and sleuth should be treated right (7) |
| SEEDED | Observe addenda occasionally specifying how top players should be treated |
| EPICURE | Fancy recipe, you said, should appeal to him (7) |
| KNEEL | Boy, it's said, should prepare to pray |
| RUE | Herb, Ophelia said, should wear it with a difference (3) |
| FIRSTCLASSMAIL | Excellent fellow, it's said - should come promptly to 2? |
| INGESTION | Eating causes heartburn, without dunking first one |
| BENARTHUR | Scottish mountain, aka 'The Cobbler' - produces dreadful heartburn (3, 6) |
| WITHALLDUERESPECT | How the Queen should be treated, if you don't mind my saying |