| DESOTO | He joined Pizarro in the conquest of the Inca Empire |
| PIZARRO | Conquistador best known for his expeditions that led to the Spanish conquest of the Inca Empire (9,7) |
| FRANCISCO | Conquistador best known for his expeditions that led to the Spanish conquest of the Inca Empire (9,7) |
| JOSHUA | In the Old Testament, Moses' successor who led the Israelites in the conquest of Canaan |
| NARSES | Byzantine general under Emperor Justinian I whose greatest achievement was the conquest of the Ostrogothic kingdom in Italy (6) |
| RISK | Game originally named "The Conquest of the World" |
| DOCKED | Craftily united in the conquest of space (6) |
| MACCHUPICCHU | Spanish forces overran and destroyed this terraced settlement perched high on a mountainside above the Urumbamba Valley in Peru, part of the Inca empire in the mid-16th century. In 1911, Hiram Bingham |
| MATILDA | She governed Normandy while her husband, William, was engaged in the conquest of England (7) |
| CUZCO | City of southern Peru; capital of the Inca Empire until the Spanish conquest in 1533 (5) |
| PERU | South American country on the Pacific which was the centre of the Inca Empire (4) |
| INCA | A ruler of the Inca Empire (or a member of his family). |
| TUPAC | Amaru who was the last ruler of the Inca Empire |
| CUSCO | Fourth largest region of Peru by area whose capital was centre of the Inca Empire (5) |
| PACHACUTI | First ruler of the Inca Empire (1438-71), for whom Machu Picchu is thought to have been built (9) |
| OBELISK | The Flaminio ---, taken to Rome from Heliopolis by Augustus to mark the anniversary of the conquest of Egypt (7) |
| DIAZ | "The True History of the Conquest of New Spain" author |
| AZTEC | Member of the Nahuatl speaking people dominant in Mexico before the Spanish conquest of the 16th century (5) |
| CONQUISTADOR | Military leader in the Spanish conquest of the New World in the 16th century (12) |
| AZTECS | Members of a people with an advanced civilization who lived in Mexico even before the conquest of Cortes |