| WVA | Harpers Ferry's locale in the Appalachian region: Abbr. |
| OLDEST | The trail is located in the Appalachian Mountains, which are among the ___ mountains on Earth and that consist of some of the most ancient crystalline rocks known (6) |
| POTOMAC | A river in the east central US, rising in the Appalachian Mountains of West Virginia (7) |
| CAMPDAVID | The US president's retreat in the Appalachian Mountains, Maryland (4,5) |
| CAMP | And 5 The US president's retreat in the Appalachian Mountains, Maryland (4,5) |
| CHEROKEE | Native American people, originally living in the Appalachian Mountains (8) |
| ANTRA | Hollow areas in the Appalachian Trail (5) |
| GAP | Cumberland ___ (narrow pass in the Appalachian Mountains) |
| BLUERIDGE | Colourful crest in the Appalachian Mountains (4,5) |
| WESTVIRGINIA | U.S. state in the Appalachian Mountains whose capital is Charleston (4,8) |
| CUMBERLANDGAP | Pass in the Appalachian Mountains, used by pioneers to reach Kentucky and Tennessee |
| HAREMS | Locales in "The Corsair" and "The Abduction From the Seraglio" |
| NEWYORK | The first section of the Appalachian Trail was opened in October 1923 in the state of ___ (3,4) |
| HELL | Frequent locale in "The Far Side" |
| JAYBIRDSTREET | Locale in the 1958 hit "Rockin' Robin" |
| DAVAO | Mt. Apo's locale, in the Philippines |
| ALEHOUSE | Frequent locale in the comic strip "Andy Capp" |
| HEAVEN | Locale in the Lord's Prayer |
| OZONE | Hole locale in the atmosphere |
| CHUNNEL | Chase scene locale in the film "Mission: Impossible" |
