| HURDYGURDY | Hard on Rudy mixing drug up with yttrium in barrel organ (5-5) |
| COUGHDROPS | Chop drugs up with love to produce lozenges (5,5) |
| ELO | Music grp. hidden in "barrel organ" |
| EMERY | Mere polluted with yttrium, a hard mineral (5) |
| NAY | Sodium with yttrium giving negative response (3) |
| DOPER | Doctor boxing athlete's drug up would be one |
| AMOS | Prophet giving drug up (4) |
| CYAN | Yttrium in a container is greenish-blue (4) |
| AUTOPSY | Gold beats yttrium in stiff test |
| ADULTERATION | Mixing drug in major quantity |
| GRENADE | Danger mixing drug in Molotov cocktail (7) |
| SEX | It shows drug's "up" times (3) |
| CHEMICAL | Caught Michael mixing drug (8) |
| ESPRESSO | Push drugs up front - ring for strong stuff (8) |
| SERINETTES | From the French for "canaries", small barrel organs formerly used to teach tunes to said songbirds (10) |
| LIFECYCLES | Iron, carbon, yttrium and chlorine found in lounges and various series of developments (4,6) |
| YESTERYEAR | Fine whiskey found in barrel back in the day |
| DEPENDABLE | Hang on, beer in barrel could be stout (10) |
| LAGERBEERS | In barrel, see brewing gallons - of these? |
| CURIO | Whether an antique musical barrel organ with a peculiar mechanism, a bizarre geological specimen, a butterfly in a glass case or a taxidermised animal in an unusual pose, it is an objet or novelty, na |