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20 answers for: Happens once again to effect cure in ruinous extre...
RANKANSWERCLUE
RECURSHappens once again to effect cure in ruinous extremes (6)
CATHEDRALBe sick - get medical man in to effect cure in church
CRUELHard-hearted way to effect cure at fifty (5)
RECURHappen once again
SALVAGESSaves from potential loss in ruinous Las Vegas (8)
DOWNFALLMiserable fellow trailed by everyone in ruinous event (8)
OPERATEWork in theatre and effect cure ultimately? (7)
ENCOREForced once again to repeat (6)
RARITYIt happens once in a blue moon
RESUMEBegin once again to make a short summary without accents
REDUCELittle Edwin takes a cure in order to lose weight (6)
REMEDYCure in mere twinkling dicky heart deficiency (6)
LAHOREHeal or cure in Asian city (6)
EALINGEffecting cure in Bow, perhaps-or part of West London (6)
ANNUALHappens once a year
REPEATHappen once more: - the performance
MUTATEWith stomach upset, took refreshment to effect a change (6)
TREATYDeal with enemy finally to effect this? (6)
ENGINEWord for cunning/skill originally, later a weapon of war; a machine, such as a locomotive, as a source of power; or, any agent to effect a purpose (6)
PUPATEYoung animal was taking food to effect a transformation