| INTER | Had a natural effect in trade etc., maybe (5) |
| ANTED | Had a natural effect in trade etc., maybe (5) |
| PETEY | He famously had a natural ring around his eye. He had leading roles in many movies, in particular the Buster Brown and Our Gang series. |
| ERODED | Damaged by a natural effect or deed, maybe |
| SHILLING | Old Bob had a natural feature to sing about (8) |
| SCIENTIST | Sit-ins etc. Maybe will involve him (9) |
| TAROTCARDS | Justice, etc., maybe from savage carrot-and-stick gal not lacking in drama? (5,5) |
| PATRONSAINT | Holy guardian of country, trade etc (6,5) |
| ECLAT | Had a striking effect in a capital ceremony, on the way back (5) |
| EMBARGOED | Imposed an official ban on trade, etc (9) |
| EMBARGO | An official ban on trade, etc (7) |
| SCATTERED | Building trades, etc., here and there? (9) |
| ORBIT | Soldiers had an effect in area of influence (5) |
| CACTI | Plants that produce an effect in the Channel Islands (5) |
| ENACT | Effect in fact can echo back (5) |
| TEXAS | State with a near-total abortion ban that went into effect in September, 2021 |
| NAFTA | Accord that went into effect in Jan. 1994 |
| KARMA | Cause and effect, in Buddhism |
| CLANK | Sound effect in Verdi's "Anvil Chorus" |
| SPLAT | Squishy impact sound effect in comics |
