| MARTINLUTHER | German monk who played a leading part in the Reformation |
| NEWLYWED | One who's just played a leading part in the match (5-3) |
| GENEVA | Swiss city, the centre of Calvinism in the Reformation |
| ROODSCREEN | Church partition surmounted by a crucifix, many of which were destroyed in the Reformation |
| ALTERCATION | Dispute Catholic leader's place in the Reformation (11) |
| HEROINE | DRUG TAKEN BY EASTERN FEMALE WITH A LEADING PART IN THE PLAY |
| BOWS | Weapons historically with a leading part in the navy |
| PROW | Officer on the point of having a leading part in shipping (4) |
| PIANOCONCERTO | Key operator has a leading part in this work (5,8) |
| AGEGAP | Silver, for example, a leading part in possible spousal separation (3,3) |
| TENOR | He may take a leading part in Britten oratorio (5) |
| MARCUSBRUTUS | Roman Senator who played a leading role in the assassination of Julius Caesar |
| BRUTUS | Roman politician who played a leading role in the assassination of Julius Caesar (6) |
| OLIVER | Rex Harrison, Sid James and Peter Sellers refused a leading part in which Lionel Bart musical? (6) |
| DIANEKEATON | US actress who played a leading role in 2018 film Book Club (5, 6) |
| MOORE | Demi - - -, actress who played a leading role in Ghost, pictured left (5) |
| HARLEQUINADE | Part of a pantomime in which a diamond-patterned buffoon or clown played a leading role, thus any piece of foolish ridiculous pantaloonery (12) |
| DOC | ___ Holliday played a leading role in the Gunfight at the OK Corral. (3) |
| SANDFORDFLEMING | He played a leading role in the construction of the Canadian Pacific Railway |
| LUTHERAN | A Protestant following the teachings of a 16th-century German monk (8) |