| STAHL | Georg Ernst -, German scientist born in 1659 who developed the phloqiston theory of combustion (5) |
| KORAN | Georg Ernst -, German scientist born in 1659 who developed the phlogiston theory of combustion (5) |
| ENGEL | Ernst, German statistician born in 1821 noted for the 'curve' named after him (5) |
| HOOKE | Robert ___, English scientist born in 1635 who built the first Gregorian telescope (5) |
| ELENA | Opera by Francesco Cavalli first performed in Venice in 1659 |
| SAGAN | Carl ***** , astronomer and planetary scientist born in 1934 (5) |
| KEPLER | Johannes ?, German scientist born in 1571 regarded as one of the fathers of modern astronomy |
| SYRTISMAJOR | Dark region of Mars observed by Christiaan Huygens in 1659 as the first documented surface feature of another planet (6,5) |
| ALBANYNEWYORK | American city that outlawed golf from its streets in 1659, marking the sport's first official mentio |
| CHEQUES | What bank documents were first issued in 1659 in London? (7) |
| TOLLER | Ernst -, German author of the stage plays Hoppla, We're Alive and The Blind Goddess (6) |
| ABBE | Ernst -; German physicist, who worked with Carl Zeiss to improve the microscope (4) |
| PURCELL | English composer, 1659-1695, who is buried adjacent in Westminster Abbey (7) |
| HEINKEL | Ernst -, German aircraft designer who died in 1958 (7) |
| DALTON | John -, English scientist born in 1766 noted for his research into colour blindness (6) |
| CATALONIA | The Principality of ____ included Perpignan between 1493 and 1659 |
| KIRCHNER | Ernst, German Expressionist painter whose works include 1910's Panama Girls (8) |
| LAPLACE | Pierre-Simon , French scholar and scientist born in 1749 (7) |
| BOGDANOR | Vernon ******** , British political scientist born in 1943 (8) |
| HENRYPURCELL | English composer 1659-95 (5,7) |
