| AETHER | Fragment of algae therapy once used as an anaesthetic by a poet (6) |
| ETHER | In 1846, what was first used as an anaesthetic by dentist William Morton? (5) |
| RETREAT | Administer therapy once again and go back (7) |
| DIATOM | Girl with a miniscule constituent of a type of algae |
| ABOARD | Love, penned by a poet on a boat (6) |
| LICHEN | Composite organism consisting of algae and fungi living symbiotically (6) |
| SCUMMY | Pond's greenish film of algae extremely murky and unpleasant (6) |
| GRAVES | Burial places depicted by a poet (6) |
| ARSENIC | Based on Persian for "gold", a toxic element with compounds including orpiment, or king's yellow as a pigment, once used as an untraceable of murder known as the king of poisons or poison of kings (7) |
| SEAOAK | Form of algae also known as rockweed |
| KETAMINE | Synthetic compound used as an anaesthetic and analgesic and also as a recreational drug (8) |
| AMYLENE | ____ hydrate was the name for a form of alcohol used as an anaesthetic until the 1950s |
| CHLOROFORM | Colourless liquid with a sweet smell used as an anaesthetic (10) |
| NACRE | Mother-of-pearl, once used as an inlay for papier-mache furniture (5) |
| DUCKINGSTOOL | Chair once used as an instrument of punishment - Old Nick got us (anag) (7,5) |
| TIGERMOTH | Biplane produced by de Havilland, once used as an RAF training plane (5,4) |
| URETHANE | Crystalline ester used as an anaesthetic and in pesticides (8) |
| NITROUSOXIDE | Colourless gas used as an anaesthetic in dentistry; its supply for recreational purposes is illegal (7,5) |
| BLOOM | A flower; a rosy colour; a healthy glow on one's cheeks; a fine powdery coating on chocolate, grapes or plums; or, a rapid seasonal flourish of algae (5) |
| LEAD | Dull, silvery grey metal once used as an anti-knocking additive for petrol (4) |