| GOLDAMEIR | First woman to be Prime Minister of Israel (5,4) |
| GANDHI | "You cannot shake hands with a clenched fist." She was the first woman to be prime minister of India. Who is this? |
| INDIRA | The only female to be prime minister of India, _ Gandhi (6) |
| LLOYDGEORGE | The only Welshman to be prime minister of the UK |
| BEEFSTEAK | Bitches gain purchase, said to be prime cut (9) |
| ETONIAN | Any former pupil of a Berkshire school, 20 of whom have gone on to be Prime Minister (7) |
| STTHERESA | First woman to be named Dr. of the Catholic Church |
| STANDBACK | 1983 top 10 hit for Stevie Nicks the first woman to be inducted twice (in 1998 and 2019) into the Rock and Roll Hall of Fame: 2 wds. |
| ALLINGHAM | Celebrated Victorian painter whose rustic rural scenes and illustrations for Hardy's Far from the Madding Crowd gained her fame and honour as the first woman to be admitted as a full member of the Roy |
| JANETRENO | First woman to be named Attorney General |
| TRUDEAU | Who has been prime minister of Canada since 2015? (7) |
| NETANYAHU | He was the first prime minister of Israel to have been born there, after its creation as a state (9) |
| EHUDBARAK | Prime minister of Israel from 1999 to 2001 (4,5) |
| BENGURION | David ?, first prime minister of Israel, from 1948-54 |
| NETANYAHJ | Prime minister of Israel (9) |
| THATCH | Pirate, having met the Queen, could be prime minister once (6) |
| THERESA | May be Prime Minister or mother (7) |
| KEITHHOLYOAKE | Only person to have been Prime Minister and Governor General (5,8) |
| ISRAEL | Country of which Benjamin Netanyahu has twice been prime minister (6) |
| TINAFEY | "You can't be that kid standing at the top of the waterslide, overthinking it. You have to go down the chute." She was the first woman to be head writer on Saturday Night Live. |