| BROKERSTIP | Financially named horse who was the only Kentucky Derby winner who never won any other race |
| COMANCHE | Horse who was the sole documented survivor of the US cavalry at the Battle of the Little Bighorn (1876) (8) |
| PESSIMISM | It "never won any battle," according to Eisenhower |
| FORCE | Power of opponent winning every other race (5) |
| COPENHAGEN | The Duke of Wellington's horse, who was buried with military honours |
| ROTBLAT | Sir Joseph ___, Nobel Peace Prize-winner who was the only physicist to leave the Manhattan Project on grounds of conscience |
| IDA | Lupino who was the only woman to direct an episode of the 1959 The Twilight Zone series |
| CHRISRYAN | British author who was the only member of the ill-fated SAS mission Bravo Two Zero to both survive and escape capture during the Gulf War |
| VALRENETWEEDIE | Who was the only Australian ballet dancer to audition successfully for the Ballets Russes companies |
| FRIEDA | Character in the comic strip Peanuts by Charles Schulz who was the only girl without a cap on Charli |
| SOLANKI | Who was the only player to make two 50+ scores in the Zimbabwe vs India T20I series? (7) |
| ADRASTUS | In Greek mythology, who was the only survivor of the Seven Against Thebes expedition? (8) |
| RODNEYGOULD | Oxfordshire rider who was the only Briton, other than Phil Read, to win a 250cc world title for Yamaha. (6,5) |
| COLBERT | Comedian who was the only man on Maxim's 2012 Hot 100 list of most beautiful women |
| ROCKYMARCIANO | Who was the only world heavyweight boxing champion to retire undefeated? (5,8) |
| FISCHER | Grandmaster who was the only US-born player to become World Chess Champion, Bobby ... |
| LEVY | Canadian who was the only actor to play in all 8 "American Pie" films |
| CILLABLACK | Who was the only female singer managed by Brian Epstein? (5,5) |
| ADRIAN | ____ IV, official title of Nicholas Breakspear who was the only English pope (6) |
| CLEVELAND | Before Donald Trump, who was the only US president elected to serve two non-consecutive terms? (6,9) |
