| UNDINE | Female water spirit conceived by the 14th-century Swiss alchemist Paracelsus; from Latin, 'little wave' (6) |
| SYLPH | Spirit of the air, as originating in the system of Swiss physician and alchemist Paracelsus (c. 1493-1541) (5) |
| WILLIAMTELL | 14th Century Swiss folk hero, seen as a symbol of rebellion against tyranny (7,4) |
| UVULA | Fleshy extension of the soft palate that hangs above the throat; from Latin, 'little grape' (5) |
| OSCULUM | Mouth-like aperture in a sponge through which water is expelled; from Latin, 'little mouth' (7) |
| LANGLAND | Piers Plowman, a great example of English literature, is said to have been written by the 14th-century poet, William ___ (8) |
| DANTEAN | Reminiscent of work by the 14th-century author of "Inferno" |
| SYLPHS | Spirits of the air, as conceived by the 16th-century Swiss physician Paracelsus (6) |
| PARACELSUS | Swiss alchemist |
| FICTIONAL | Conceived by the imagination (9) |
| BANC | Prohibition is first conceived by the judges' bench (4) |
| RETICULUM | Small southern constellation between Dorado and Hydrus; Latin, 'little net' (9) |
| NIXIE | Unfriendly female water-spirit |
| ONDINE | Female water spirit |
| ALKAHEST | Hypothetical universal solvent sought by the alchemists, originating in the writings of the Swiss physician Paracelsus (1493-1541) (8) |
| AZOTH | Alchemical name for mercury, and of the panacea postulated by Paracelsus in the 16th century (5) |
| AMISH | The US and Canadian Mennonite sect tracing its roots from a 17th-century Swiss bishop (5) |
| CRAB | What female water creature releases up to 1.5 trillion eggs into the ocean each year? |
| ALCHEMIST | The claims that could be made by such as Paracelsus (9) |
| BUS | "Desert ___" (satirical video game conceived by Penn and Teller involving a drive from Tucson to Las Vegas) |
