| WRAY | Fay of "The Most Dangerous Game" |
| LYALL | Gavin ___, author of the action thriller The Most Dangerous Game |
| HUMANS | Big-game hunting targets in the classic short story "The Most Dangerous Game" |
| LAWNDARTS | Former picnic game that should've been titled "The Most Dangerous Game" |
| COOKSTRAIT | Body of water considered one of the most dangerous in the world, named after a naval commander (4,6) |
| FUNNELWEB | One of the most dangerous group of spiders, native to Australia (6-3) |
| GRIZZLYBEAR | Known to be one of the most dangerous animals in Canada |
| JUMPTHESHARK | "... ___. It's our most dangerous game, and this fierce fish is ready to strike. Only our most acrobatic contestants will survive!" |
| LIAM | Hemsworth in "Most Dangerous Game" |
| CHRISTOPHWALTZ | Spectre actor nominated for an Emmy for starring in Quibi's Most Dangerous Game: 2 wds. |
| GORBALS | Area in Glasgow which during the 1930s was called the most dangerous place in the UK (7) |
| HURRICANE | The most dangerous form of natural disasters |
| BROWN | The most dangerous type of bear, to humans (5) |
| FRONTLINE | In the trenches; the most dangerous position (5,4) |
| INSECTS | Small, invertebrate creatures, the most dangerous in Mallorca are the pine processionary caterpillars which have toxic hairs on their body that can cause skin or allergic reactions in humans and are p |
| LEARY | Doctor whom Nixon called "the most dangerous man in America" |
| HAIRIEST | I hear it's possibly the most dangerous |
| DICIEST | The most dangerous Democrat here is French |
| NIXON | President who called Dr. Timothy Leary "the most dangerous man in America" |
| AUTOMOBILE | Ray Bradbury called it "the most dangerous weapon in our society" |
