| SPECIMEN | Example of animated epic with humans chasing monsters, ultimately (8) |
| OGRES | Monsters ultimately hiding amid mineral deposits (5) |
| GROENING | Creator of animated comedy The Simpsons, Matt -------- (8) |
| DIAMANTE | From French, meaning literally "set with diamonds", what word is an anagram of animated? (6) |
| FANTASIA | Ardent admirer attends, backing opening of animated film |
| NORTHMAN | Viking-based epic with Anya Taylor-joy, The _ (8) |
| ENCIPHER | Encrypt epic with new hero sacrificing nothing strangely (8) |
| ODYSSEYS | Ancient epic with first saga taken on long journeys (8) |
| ARTEFACT | Something known to be associated with human skill and endeavour, primarily? (8) |
| CHERUBIM | Winged creatures with human faces (8) |
| THREATEN | Intimidate team leader with Human Resources over a teen delinquent (8) |
| ICEPICKS | Runner returns around country's first epic with climbing equipment (3,5) |
| APE | Animal that shares around 99% of its DNA with humans |
| TRAIN | How To ___ Your Dragon, series of animated films with the voice of 47D (5) |
| CREWED | With humans on board, as a space flight |
| BOT | Program built to interact with humans online |
| SABERTOOTH | Extinct wildcat that may have coexisted with humans |
| DOMESTICATION | Tameness, adaptation to life with humans (13) |
| CAPTCHA | How some sites find out if they're dealing with humans or robots (7) |
| BIGAPES | They may have coexisted with humans |