| PINEAL | Endocrine gland in the brain that produces the melatonin responsible for regulating sleep patterns and circadian rhythms (6) |
| REALM | Domain almost entirely encountered in sleep pattern? |
| THYROID | One of the largest endocrine glands in the body (7) |
| THYROIDS | Butterfly-shaped endocrine glands in vertebrates (8) |
| PINEALGLAND | A pea-sized organ in the brain that secretes melatonin into the bloodstream (6,5) |
| DOPAMINE | A chemical in the brain that acts as a neurotransmitter (8) |
| DESIGN | A decorative pattern; a blueprint, plan or sketch indicating the intention for something; a finished artistic creation; or, a scheme fashioned in the mind (6) |
| HYPOTHALAMUS | Section of the brain that produces many hormones (12) |
| REPEAT | A copy; a motif duplicated in a pattern; a retracing of one's course; or, a second, third, fourth etc broadcast of a radio/television programme (6) |
| PITUITARY | The master endocrine gland, attached by a stalk to the base of the brain (9) |
| BALANCE | A pair of scales held by a statue of justice or used as a symbol of Libra; a device for regulating the speed of a clock or watch; or, equilibrium (7) |
| PANCREAS | A large gland in the upper part of the abdomen that secretes insulin (8) |
| PANAMA | The names of which two countries have the letter pattern - A - A - A? (6) |
| CANADA | The names of which two countries have the letter pattern - A - A - A? (6) |
| OCCIPITAL | Lobe in the brain that handles visual processing |
| SHUTTER | A louvred or solid wood panel for an external or internal window; or, a device for regulating the opening of a camera's aperture (7) |
| OBLONGATA | Medulla ........., the part of the brain that is responsible for involuntary functions such as sneezing (9) |
| WHIRL | A brief dance or trip; a pirouette; a spiralling pattern; a rapid series of social engagements; or, a tumult (5) |
| MEDULLAOBLONGATA | That part of the brain that tapers off into the spinal cord (7,9) |
| CEREBELLUM | A part of the brain that controls the body's movements and balance (10) |