| DUPIN | Edgar Allan Poe's fictional detective that served as a prototype for a genre of investigators, C Aug |
| MIRA | From the Latin meaning "wonderful" or "astonishing", a pulsating variable red giant in Cetus the Whale that serves as a prototype for its own class of stars (4) |
| CONCEPTART | Visual prototype for a piece of media |
| JETHRO | 18th-century English agricultural pioneer - his seed drill machine was a prototype for all future sowing implements (6,4) |
| GLEBE | From Latin for "clod", a plot of land attached to a parish church that served as part of a clergyman's benefice; or, a poetic word for fields or the soil (5) |
| MIR | The name of the Soviet/Russian modular space station that served as a versatile space laboratory for more than 14 years, starting in 1986, before ground controllers forced it down into the Pacific Oce |
| FORTMACKINAC | Old military outpost that served as a battle site during the War of 1812 (Michigan) |
| OVALTINE | Chocolate malt drink mix that served as a bit for Bania's stand-up comedy act in "Seinfeld" |
| PLUTO | God of the underworld identified with Hades; the name of a cat in Edgar Allan Poe's short story The |
| SALYUT | The name for any of a series of Soviet space stations (of two designs), launched between 1971 and 1982, that served as living quarters and scientific laboratories or military reconnaissance platforms. |
| COMPANION | One of a pair of investigators primarily working on a swindle involving money, power and head of AIG (9) |
| ROMCOM | Informal name for a genre of film commonly made by Richard Curtis (6) |
| UTAH | State that served as a filming location for "Touched by an Angel" |
| AGORA | Open square that served as a meeting place or market in an ancient Greek city |
| TRIPOLIHARBOR | North African coastal area that served as a naval battleground during the First Barbary War (Hawaii) |
| RAP | Average returns for a genre of music (3) |
| ROMANTASY | Portmanteau for a "genre of swords and soulmates," per the Guardian |
| AGRA | City of northern India that served as capital of the Mughal empire under such leaders as Shah Jahan (4) |
| GRANTCHESTER | British series about a priest and a detective that premieres its fourth season this week on PBS |
| USHER | Edgar Allan Poe's tale, The Fall Of The House Of ... |