| ROSH | Due to the unusual structure of this grid, please note the following for solving in Across Lite A |
| REAL | Although this puzzle can be solved in Across Lite, the print version includes elements that cannot b |
| ADVERTISER | Refer to the unusual rise, one to make public (10) |
| NIB | Tip for solving in ink? |
| RETINUE | Reunite the following for a change (7) |
| CHEAT | Use Across Lite's "Check" or "Reveal" feature, e.g. |
| ENIGMA | Puzzle-solving in game (6) |
| CROSSWORDPUZZLE | What you're solving (in more ways than one, based on the starts of 17-, 26-, 38- and 48-Across) |
| INDIGO | 1905 Nobel winner Adolf von Baeyer derived the molecular structure of this distinctive blue dye extracted from a plant of the same name, which is used in textiles and printing |
| DUALIPA | "Dance the Night" singer ... or, parsed differently, a hint to the pair of drinks in row 3, 5, 11 or 13 of this grid |
| DNA | Rosalind Franklin was a pioneer in revealing the molecular structure of this nucleic acid (1,1,1) |
| INSULIN | After 35 years of research, Chemistry Nobel winner Dorothy Hodgkin determined the structure of this well-known hormone made by the pancreas |
| PENICILLIN | Dorothy Crowfoot Hodgkin, winner of the 1964 Nobel Prize, discovered the structure of this antibiotic which was originally discovered by Alexander Fleming |
| HIP | Saurischian and ornithischian dinosaurs are separated from one another by the structure of this part of the body. |
| ZAMBONI | Machine waiting to enter the middle of this grid, as suggested by the answers to the starred clues |
| PARTRIDGE | With the contents of this grid's circles, part of the refrain in 3-/6-/9 |
| QUANTUM | Work of scientist at The Perimeter Institute may document lacquer's unusual structure (7,15) |
| PISA | Site of a famous (see circled letters) that the right half of this grid resembles |
| EDGES | Parts of this grid with three examples of our theme entries ... just follow the directions to find them |
| WELSHRAREBIT | No honour in paying for the unusual bit at the end of snack (5,7) |
