| OD | Drug tragedy, for short |
| GENRES | Romance and tragedy, for two |
| LEAR | Tragedy for comic writer |
| DOWNPLAY | Make little of sad tragedy, for instance (8) |
| REGAN | Daughter in tragedy, for example, raced around (5) |
| PAYABLE | Outstanding story ending in tragedy for Romeo (7) |
| ACCIDENT | Unfortunate tragedy for The Papers in a manner of speaking (8) |
| PROMETHEUSBOUND | It's a tragedy for sure, having ruined them with use (10,5) |
| MUNICHAIR | First off, grim United crash is a tragedy for 13Ac 23Dn (6,3,8) |
| DISASTER | First off, grim United crash is a tragedy for 13Ac 23Dn (6,3,8) |
| THESPIAN | Word, from the name of a dramatic poet regarded as the founder of Greek tragedy, for an actor (8) |
| DRAMA | A comedy or tragedy, for example, symbolised by the masks of Thalia and Melpomene; plays as a genre or literary style; or, histrionics generally (5) |
| KINGLEAR | Tragedy of monarch at meadow, heading for Runnymede |
| HELLO | Jealous man losing love, heading for tragedy that's unexpected (5) |
| MERCUTIO | Part for performer cut - I offer role in tragedy (8) |
| ELECTRA | Eugene O'Neill updated the Greek tragedy of Agamemnon's daughter for his 1931 play, Mourning Becomes |
| GREEDY | Wanting as much as possible for both sides of Greek Tragedy (6) |
| EMMY | Short novel ending with tragedy gets American award (4) |
| BEAUMONT | Dramatist noted for his collaborations with John Fletcher such as The Woman Hater, Philaster and The Maid's Tragedy (8) |
| CALAMITY | Embattled mission cut short in town leading to tragedy |