| HOLMES | Doyle's Sherlock |
| MORIARTY | Professor _, archenemy of Conan Doyle's Sherlock Holmes (8) |
| MYCROFT | Older brother of Sir Arthur Conan Doyle's Sherlock Holmes (7) |
| ASTUDYINSCARLET | Debut novel of Arthur Conan Doyle's Sherlock Holmes and Dr. Watson, published in 1887 (1,5,2,7) |
| REDHEADED | Eponymous League investigated in the second of Sir Arthur Conan Doyle's Sherlock Holmes short stories (3-6) |
| SIGN | The _ of the Four: written in 1890, the second of Arthur Conan Doyle's Sherlock Holmes novels (4) |
| THEHOUNDOFTHE | Sherlock Holmes and Dr Watson investigate a crime on the moors in Conan Doyle's ... Baskervilles (3, |
| STUDY | A - in Scarlet; Sir Arthur Conan Doyle's first novel to feature Sherlock Holmes and Dr Watson (5) |
| LASSUS | Celebrated in a matinee at the 2015 Proms, composer whose "polyphonic motets" are a favourite of Sir Arthur Conan Doyle's character Sherlock Holmes (6) |
| BAKERSTREET | London street inhabited by Sherlock Holmes in Conan Doyle's stories (5,6) |
| DOCTORWATSON | Sherlock Holmes's friend and assistant in Sir Arthur Conan Doyle's stories (6,6) |
| THEVALLEYOFFEAR | Conan Doyle's last Sherlock Holmes novel (3,6,2,4) |
| ELEMENTARY | TV series with Jonny Lee Miller and Lucy Liu which is a modern-day take on Sir Arthur Conan Doyle's character Sherlock Holmes |
| WATSON | Sherlock Holmes' assistant in Arthur Conan Doyle's books including The Hound of the Baskervilles (6) |
| BELL | Surgeon who partly inspired Arthur Conan Doyle's character Sherlock Holmes; or, any one of a series of musical instruments forming the chime of a carillon (4) |
| HORNUNG | Sir Arthur Conan Doyle's brother-in-law who created Sherlock Holmes's supposed "criminal twin" Raffles (7) |
| ACASEOFIDENTITY | Third of Sir Arthur Conan Doyle's 56 Sherlock Holmes short stories, published in 1891 (1,4,2,8) |
| SCARLET | Doyle's "A Study in ___" |
| ASTUDY | Doyle's "___in Scarlet" |
| CONAN | Doyle's middle name |
