| SIGNALTOWER | Director of railway trains |
| GUARD | Person in charge of a railway train (5) |
| IRRITANT | In the beginning, Indian Railway train carrying tritium derailed, producing a source of discomfort (8) |
| ORIENTEXPRESS | Famous railway train (6,7) |
| EXPRESS | Fast railway train (7) |
| CHOOCHOO | Child's railway train (4-4) |
| SECONDARYSCHOOL | For teaching teenagers to back up a railway train (9,6) |
| CHELTENHAMSPA | MEP health scan reveals fault, so Great Western Railway train could take him here to recover (10,3) |
| PUFFPUFF | A traditional African beignet- or doughnut-like deep-fried snack; or, a child's word for a "choo-choo", aka railway train/steam locomotive (4-4) |
| GREATWESTERN | ____ Railway, train company whose Night Riviera service runs from London to Penzance (5,7) |
| TRAIN | Word for a dragging part of a robe originally, later a caravan of camels, line of gunpowder, series of railway carriages or sequence of thoughts (5) |
| RAKE | A hay- or grass-gathering tool; a thin horse; a herd of colts; a string of wagons; a train of railway carriages; or, a debauched man of fashion, aka roue (4) |
| THOMAS | Engineer who built thousands of miles of railway in the 19th century - including the Lancaster & Carlisle Railway and the Great Northern (6, 7) |
| BRASSEY | Engineer who built thousands of miles of railway in the 19th century - including the Lancaster & Carlisle Railway and the Great Northern (6, 7) |
| KNUR | Knot of railway workers by end of track |
| TRAINSPOTTER | Collector of the numbers of railway locomotives (12) |
| LOCKE | Civil engineer ranked as one of the pioneers of railway development (5) |
| GESTATION | Development of plan, say, to be mounted in front of railway terminal |
| HEATHERY | Moorland east of railway having flecks of various colours (8) |
| GAUGE | Distance between the rails of a line of railway track, standardised in Britain and elsewhere as 4ft 8.5 in (5) |
