| IPHONE | Device used with the actions at the ends of the starred answers |
| PHARMACOLOGY | Branch of medicine dealing with the actions of drugs in the body (12) |
| DECKOFCARDS | Something with which you might do the actions at the ends of 20-, 27- and 45-Across |
| FIVETOOLPLAYERS | Term for people who can do all the actions at the starts of 17-, 22-, 35-, 42- and 48-Across |
| ACUTE | Keen for a piece of the action at the end of June (5) |
| EXTORTION | Old lover with the action of a twister said to be taking too much money (9) |
| ANTAGONIST | Biochemical substance that interferes with the action of another (10) |
| VALEDICTION | A farewell involving devil with the action (11) |
| BOARDGAMES | Low-tech pastimes involving the actions seen at the end of the *clue answers |
| WHOSTHERE | Response to the sounds at the ends of the starred answers |
| WHESTHERE | Response to the sounds at the ends of the starred answers |
| COMB | A bee's structure for storing honey; a wool-spinner's device used with a card; an implement used as a hair detangler or a homemade kazoo; or, the crest of a chicken/hen (4) |
| RAMROD | A device used with early firearms to push the charge into the barrel (6) |
| ONBROADWAY | 1963 hit for the Drifters ... or where you can see the ends of the starred answers |
| LOWRIDERS | Cars close to the ground, and a hint to the ends of the starred answers |
| CODEWORDS | Lexicon used by spies, and a key to the ends of the starred answers |
| GOOGLEDRIVE | Cloud storage option whose apps are featured at the ends of the starred clues' answers |
| GETONBOARD | "Join the team," or what you might do to the ends of the starred answers |
| TONEDOWN | Make milder, or an apt description of the ends of the starred answers |
| TACKLEBOX | Container in which you'd find the items at the ends of the starred clues |