| SPANISHFLU | Devastating outbreak involving strange pains and bizarre flush (7,3) |
| PARANORMAL | Involving strange, unknown forces that cannot be explained by scientific laws (10) |
| SLE | An inflammatory disease of connective tissue with variable features including fever and weakness and fatigability and joint pains and skin lesions on the face or neck or arms. |
| TRUMPET | Instrument festival involving strange piano (7) |
| LIBRETTO | Text of opera involving strange lot with tribe (8) |
| AGONY | Throes, pains and woes, together |
| KIRK | Cameron of "Growing Pains" and "Left Behind: The Movie" |
| ALLAN | Poet and writer of the macabre and bizarre, Edgar ... Poe |
| FREAKY | Fellow about to find a king variable and bizarre (6) |
| GIGANTIC | Very great job that's temporary and bizarre |
| GARGOYLE | Outburst about awfully gory and bizarre ornament |
| SURREAL | Small, ancient city, authentic and bizarre (7) |
| NIGHTMARISH | Bloodcurdling and bizarre |
| PINACOLADA | Manage a pain and a cold with a cocktail (4,6) |
| MASOCHISTS | They thrive on pain and suffering |
| RHEUMATOID | _ arthritis, condition causing pain and swelling in the joints (10) |
| FRIDAKAHLO | Mexican painter who starkly portrayed pain and the harsh lives of women: 2 wds. |
| RHEUMATOLOGY | The study of pain and stiffness in muscles and joints (12) |
| IBS | Condition involving abdominal pain and diarrhoea or constipation (1,1,1) |
| REBELWILSON | Australian actress and writer whose films include Pain & Gain, How to Be Single, Pitch Perfect, Bridesmaids, Ghost Rider and Night At The Museum: Secret Of The Tomb (5,6) |