| EXTINCTION | Destruction or loss of a species |
| TURNOVER | Word for transference; a pasty-like triangular pie made by folding one half of the crust around a filling of apple or jam; a small shawl; profit, revenue or yield; or, loss of possession of the ball t |
| CATS | Domesticated felines known collectively as a destruction or pounce or a kindle/litter when young (4) |
| WHITECAP | A bird with a pale crown, such as the male of a species of redstart; or, a crested wave or breaker (8) |
| LESION | Injury or change in an organ or tissue tending to result in impairment or loss of function |
| DISGRACE | Shame or loss of favour or respect (8) |
| AKINESIA | Impairment or loss of the power of voluntary movement |
| RUINATION | State of destruction or collapse |
| TRURO | Birthplace in Cornwall of actor Samuel Foote, whose loss of a leg in a riding accident is sometimes attributed the origin of the theatrical phrase "break a leg!" (5) |
| ORRIS | Root of a species of iris used in perfumery; or, a form of gold or silver lace used as an edging (5) |
| LARYNGITIS | Inflammation of the voice box, resulting in huskiness or loss of voice (10) |
| INSURE | To plan for recompense in case of damage to or loss of property (6) |
| ADIABATIC | Occurring without gain or loss of heat |
| DISASTER | Event causing great damage or loss of life (8) |
| APHAGIA | Refusal or loss of the ability to swallow (7) |
| PERISHED | Suffered destruction or ruin (8) |
| RUINOUS | Causing destruction or destitution |
| MAYHEM | Violent destruction or confusion (6) |
| PINECONE | Depicted in paisley patterns or as a finial, the strobilus of a species of conifer that can be used as a home-made weather station (8) |
| ALLHEAL | Name of a species of betony, prunella or valerian that refers to the reputed medicinal, restorative or therapeutic qualities of said herbs (7) |