| UGLYCUSTOMER | Dangerous enemy is a challenge to the beautician (4,8) |
| ARCHFOE | Unsettling reach of dangerous enemy |
| ADEADLYFOE | Deaf Doyle composed article about dangerous enemy (1,6,3) |
| LACAN | "Television: A Challenge to the Psychoanalytic Establishment" author Jacques |
| HARDCASE | Tough guy is a challenge to legal team? |
| DEFECT | To go over to the enemy is a fault |
| PLEATEDSKIRT | Parochial-school attire that's a challenge to iron |
| TREWS | "Enemy" is a current 2022 song by The ___, the rock band from Antigonish, Nova Scotia |
| JIGSAWPUZZLE | It's a challenge to reassemble wasp crushed in first of juleps I quaff |
| ELMO | Sesame Street star whose enemy is a rock |
| CLIMATE | Melting sea ice means more Pacific walruses are resting on land, further from their feeding grounds so the greatest challenge to the survival of the walrus is ___ change |
| GAGE | An old word for a pledge, such as a glove, flung down as a symbol of a challenge to combat; or, the Baronet of Hengrave credited with introducing a damson-, mirabelleor plum-like green fruit to Englan |
| GAUNTLET | Baking a gluten tart initially is a challenge (8) |
| DARED | Issued challenge to the dead perhaps, right in the centre (5) |
| RACEME | What was the tortoise's challenge to the hair? (4,2) |
| ICEBUCKET | Bar accessory is a challenge (3,6) |
| FRAN | Drescher of "The Beautician and the Beast" |
| STRETCHER | Patient carrier's challenge to the Queen (9) |
| NAILVARNISH | A quick coating offered by the beautician? |
| COMEGETME | Holed-up suspect's challenge to the cops |