| DESPERATEDAN | Cow pie-eating character who appeared in The Dandy from its first issue in 1937 to its final issue in 2013 |
| YOU | Word sometimes shortened to its final letter |
| DESPERATE | Cow-pie-eating Wild West comic character, introduced in 1937 (9,3) |
| ORISON | Alternative is first issue in prayer |
| STRIPOFF | Remove the gear from small dandy from Split (5,3) |
| SETOFF | Start with dandy from the home counties |
| SONIC | Issue I see connected with the sound (5) |
| SEMITONE | Skinhead has issue, I note (8) |
| RUIN | Foundering erection is issue, I admitted |
| INDECISIVE | Not settling an issue (I, not U) |
| MISERERE | Psalm 51 (50 in the Vulgate); from its first word, meaning 'Have mercy' in Latin (8) |
| THOR | Superhero with a hammer who appeared in the first issue of the comic book The Avengers |
| SHERLOCKHOLMES | Character who appeared to meet his end in The Final Problem (1893) |
| SNOOTY | Lord _; character who appeared in the Beano (6) |
| FALSTAFF | Shakespearian comic character who appeared in four of the bard's plays (8) |
| MICKEYMOUSE | Walt Disney cartoon character who appeared in the 1928 film Steamboat Willie (6,5) |
| SATURDAYEVENINGPOST | 1821: The ___ publishes its first issue (covers by Norman Rockwell would come about a century later) |
| READERSDIGESTMAGAZINE | The Library's Periodicals Room was the source of most of the excerpted material in the first issue o |
| DUKEOFWINDSOR | Title in the peerage of the United Kingdom only ever used by one person, from 1937 to 1972 (4,2,7) |
| SPOCK | Only character who appeared in every episode of "Star Trek" |