| SOUTHAFRICA | Country thought to be the source of a highly infectious Covid-19 variant (5,6) |
| HRVATSKA | Croatian name for that country, thought to derive from proto-Ossetian (8) |
| DOCTOR | An old word for a teacher; slang for a ship's cook; a cool sea breeze in a warm country, thought conducive to health; a surgeonfish; a "sawbones" known to the Anglo-Saxons as a leech; brown sherry; or |
| DELTA | Covid-19 variant of note |
| OMICRON | Dangerous COVID-19 variant |
| AMERICANPIE | Recipe mania may be the source of a popular song (8,3) |
| EPONYM | What do we call a person whose name is thought to be the source of the name of a city, country, etc (6) |
| DYERSROCKET | Eurasian plant in the genus Reseda once cultivated as the source of a bright yellow dye (5,6) |
| URHAMLET | Lost manuscript said to be the source of a Shakespeare classic |
| STATESECRET | Subject of a highly classified file |
| THIRDEYE | A brain's pineal gland, believed by some to be the source of spiritual insight; or, the Ajna chakra through which to gaze in yogic drishti (5,3) |
| AMBROSIA | Food of the gods in Greek mythology, said to be the source of their immortality (8) |
| ORYX | Animal some believe to be the source of the unicorn myth |
| BABEL | Which Old Testament tower is meant to be the source of the world's languages? (5) |
| PESTILENCES | Epidemic outbreaks of deadly and highly infectious diseases (11) |
| MYXOMATOSIS | Highly infectious disease of rabbits (11) |
| STOCKPOT | Northern town has no right to be the source of many soups |
| TREE | Arrest chemist that's turned out to be the source of dropped needles (9,4) |
| CHRISTMAS | Arrest chemist that's turned out to be the source of dropped needles (9,4) |
| COCONUT | Fruit that can be the source of the starts of the answers to starred clues |