| GATEWAY | Computer manufacturer which closed down its Irish operation in 2001 with the loss of almost 1,000 jobs. (7) |
| LEEGREENWOOD | I.O.U. singer who had a hit in 2001 with God Bless the U.S.A.: 2 wds. |
| PLANETOFTHEAPES | 1968 sci-fi film remade in 2001 with Mark Wahlberg |
| HTML | Backed up the almost 1,000-line web code (4) |
| SWORDFISH | John Travolta action thriller from 2001 with Halle Berry (9) |
| SWEDEN | Country almost 1,000 miles long |
| OSLO | Norwegian city founded almost 1,000 years ago |
| OAK | The battleship Royal ... was torpedoed at Scapa Flow in October, 1939, and sank with the loss of 800 lives |
| THRESHER | Which US nuclear submarine foundered in 1963 with the loss of 129 crew? (8) |
| KURSK | Which Russian nuclear submarine foundered in 2000 with the loss of 118 crew? (5) |
| ALAMO | Mission and fortress compound in San Antonio, Texas besieged by Mexican forces in 1836 with the loss of all defenders (5) |
| SCAPA | The British battleship Royal Oak was torpedoed at ... Flow in October, 1939, and sank with the loss of 800 lives |
| LUSITANIA | Cunard liner torpedoed and sunk in 1915 by a German U-boat, with the loss of 1195 lives (9) |
| EAT | Chain of sandwich shops with an imperative name, which closed its UK stores in 2020 (3) |
| TIMEX | Owner of the Dundee plant which closed after 47 years in 1993, scene of a major industrial dispute (5) |
| AMNESIC | With the loss of a large block of interrelated memories (7) |
| OBSTACLE | Former pupils had to come to grips with the loss of Kelvin. It's a stumbling block (8) |
| SUNBEAM | West Midlands motor manufacturer which became part of the Rootes Group in 1935 |
| BLOSSOM | Mob taken aback with the loss of a flower (7) |
| WALTERZELLER | Founder of a Canadian discount retail chain which closed in 2013: 2 wds. |