| BOBNEWHART | Comedian who appeared several times as Professor Proton in The Big Bang Theory |
| ALFALFA | All but outer parts of Cornish flower used several times as fodder plant |
| NEUTRON | Counterpart of a proton in an atomic nucleus |
| BOB | Newhart who played Professor Proton on "The Big Bang Theory" |
| EIGHTY | Number of electrons or protons in an atom of mercury (6) |
| TWO | Number of protons in a helium atom |
| EMMATHOMPSON | Who appears as Professor Trelawney in Harry Potter and the Prisoner of Azkaban and Harry Potter and the Order of the Phoenix? (4,8) |
| MIRIAM | First name of the actress who starred as Professor Sprout in the Harry Potter films (6) |
| ERNIEWISE | Comedian who appeared with his father in the 1930s as "Bert Carson and his Little Wonder" |
| BERNIEMAC | Stand-up comedian who appeared as Frank Catton in the “Ocean’s” films |
| ANCONA | Ronni ___, comedian who appeared in The Big Impression (6) |
| AMANDA | Who appeared as Professor Sam Ryan in TV'S Silent Witness? (6,6) |
| BURTON | Who appeared as Professor Sam Ryan in TV'S Silent Witness? (6,6) |
| DONMACLEAN | Comedian who appeared on the BBC TV series Crackerjack with Michael Aspel, Peter Glaze and Jan Hunt in the 1970s |
| MERTON | Paul -, comedian who appeared on TV series Who Do You Think You Are? in August (6) |
| PETERSELLERS | English actor and comedian who appeared in the film Being There (5,7) |
| LENNY | _Henry, comedian who appeared on The Masked Singer in 2021 (5) |
| GOLDBERG | US comedian who appeared in Star Trek: The Next Generation, Whoopi _ (8) |
| JOELYCETT | Comedian who appeared at the BAFTAs dressed as Queen Elizabeth I (3,6) |
| BENNYHILL | English comedian who appeared in 1969 film The Italian Job (5,4) |