| NEWPORT | City in South East Wales, on the River Usk (7) |
| CLWYD | A former county in North East Wales, on the Irish Sea (5) |
| NEWTOWN | Largest town in Powys, Wales, on the River Severn (7) |
| SILURES | Ancient tribe of what is now south-east Wales, offering fierce resistance to the Romans (7) |
| YONKERS | A city in South East New York State, on the Hudson River (7) |
| DETROIT | City in south-east Michigan on a river of the same name (7) |
| AVIGNON | A city in South East France, on the Rhone; seat of the Papacy from 1309 to 1377 (7) |
| DRESDEN | Industrial city in South East Germany on the River Elbe, twinned with Coventry since 1959 (7) |
| RANGOON | Former capital city in south-east Asia (pop about 7 million), founded in the 11th century (7) |
| CAERLEON | Welsh town on the River Usk in the northern outskirts of Newport (8) |
| ABERGAVENNY | Market town in Monmouthshire, Wales, on the north bank of the River Usk housing an 11th-century castle (11) |
| SWANSEA | City in Wales, on the Bristol Channel (7) |
| ETIENNE | St -------, industrial city in south-east central France (7) |
| HOLDALL | Accommodating people from Usk initially trapped in 21 (7) |
| HELPFUL | Accommodating people from Usk initially trapped in 21 (7) |
| USK | Game-fishing river in south-east Wales (3) |
| EBBWVALE | Industrial town in south-east Wales (4,4) |
| CARMARTHEN | Town in SW Wales on the River Towy (10) |
| LLANDOVERY | Market town in Carmarthenshire, Wales, on the River Tywi |
| MOLD | Town in Flintshire, North Wales, on the River Alyn |
