| BARNARD | Christiaan ___, South African surgeon who performed the first human heart transplant in 1967 (7) |
| SMUTS | Jan Christiaan ___, South African statesman; prime minister 1919-24 and 1939-48 (5) |
| SURGERY | Back in 1893, African-American cardiologist Daniel Hale Williams performed the first successful open heart _ |
| BREATHE | Be alive and be having a heart transplant in (7) |
| DIDDLES | Cheats the French having performed the first dance before them (7) |
| LOUISWASHKANSKY | Patient who was the world's first to receive a heart transplant in 1967 (5,10) |
| INTROIT | At home, trio performed the first psalm (7) |
| HUYGENS | Dutch polymath Christiaan ____ invented the pendulum clock and discovered Titan, Saturn's largest moon |
| BESSEL | Who performed the first accurate measurement of the distance to a star and predicted the existence of Neptune (6) |
| LEONOV | Cosmonaut Aleksei who performed the first space walk |
| SELENAGOMEZ | Only Murders in the Building actress who received a kidney transplant in 2017: 2 wds. |
| ABRUPT | Sudden belch after heart transplant in outskirts of Ashgabat |
| ESTHER | Student who had to undergo a liver transplant in Hollyoaks (6,5) |
| CARLA | ___ Connor, in desperate need of a kidney transplant in Coronation Street (5) |
| LARRYHAGMAN | Dallas actor who received a liver transplant in 1995: 2 wds. |
| OSCAR | Son of Gail Loman who needs a bone marrow transplant in Emmerdale (5) |
| JADE | ___ Green, Dean Wicks's daughter who needs a transplant in EastEnders (4) |
| THORNE | Dr ___, involved in Peter Barlow's liver transplant in (6) |
| REPOT | Transplant in the greenhouse |
| MANDYPATINKIN | Homeland actor who received cornea transplants in 1997 and 1998: 2 wds. |
