| VANTULLEKEN | Chris and Xand _ _, siblings, medics and TV colleagues (3,8) |
| VAN | & 12 Across Chris and Xand _ _, twins and Planet Child hosts (3,8) |
| JUDITH | Mark Durden-Smith's mum and TV colleague, _ Chalmers (6) |
| FINNIGAN | Judy ___, Richard Madeley's wife and TV colleague (8) |
| WILLIS | Imogen and Joshua __, siblings who live together on Ramsay Street (6) |
| TWIN | In Emmerdale, Heath and Cathy Hope are ___ siblings (4) |
| SPIRITINTHESKY | Song that gave Norman Greenbaum, Doctor and the Medics and Gareth Gates number one singles in the UK |
| FACEMASK | Confront first of medics and demand something to stop germs spreading |
| INLAW | Sister-___ (sibling of one's husband, say) (hyph.) |
| RORYBREMNER | TV colleague of John Bird and John Fortune, 1999-2010 |
| OUCH | Operation ----!, CBBC show hosted by Chris and Xand van Tulleken (4) |
| LOISGRIFFIN | 21st century TV mother of Meg, Chris and Stewie, married to Peter |
| TAKEUMBRAGE | Consider fashion, following posh medic, and show resentment |
| PREDICAMENT | Difficult situation upsetting medic and parent (11) |
| ROCKBOTTOMS | Chris and Timothy's lowest levels? |
| MADDOW | TV colleague of Hayes and O'Donnell |
| LOSE | Dr Xand Van Tulleken show: How To _ Weight Well (4) |
| ARTE | TV colleague of Goldie and Lily |
| STEVEN | TV colleague of Randy and Jennifer |
| DEFUNCT | TV colleague restricting enjoyment with Ant finally, no longer working (7) |
