| HAWORTH | Chorley-born scientist who was the first person to make a vitamin artificially when he synthesised v |
| FORGETMENOT | Remember the first person to make a bloomer (6-2-3) |
| EARHART | Second person to make a solo transatlantic flight |
| EASEL | Wife leaves treacherous person to make a stand |
| JENNER | Edward - - -, English scientist who was the first doctor to introduce and study the smallpox vaccine (6) |
| MARIECURIE | Scientist who was the first female professor at the University of Paris: 2 wds. |
| HAWKING | Scientist who was the subject of 2014 film The Theory of Everything (7) |
| EINSTEIN | German-born scientist who won the Nobel Prize in Physics in 1921 for his explanation of the photoelectric effect (8) |
| BRONOWSKI | Polish-born scientist who wrote and presented the BBC TV series The Ascent of Man in 1973 (9) |
| CURIE | Scientist who was the first double Nobel laureate |
| RICE | Condoleezza ___ (b 1954), political scientist who was the US Secretary of State (2005 2009) |
| WENHOLEE | Author of 'My Country Versus Me: The First-Hand Account by the Los Alamos Scientist Who Was Falsely |
| INVENT | Be the first person to make something (6) |
| IMPOSE | First person to make up poems to enforce (6) |
| ADRIAN | Edgar ___ (1889 - 1977), London-born scientist who won the Nobel Prize for Physiology in 1932 (6) |
| APPLETON | Edward ___ (1892-1963), Bradford-born scientist who won the Nobel Prize for Physics in 1947 (8) |
| THOMSON | J J ___ (1856 - 1940), Manchester-born scientist who won the Nobel Prize for physics in 1906 (7) |
| YURIGAGARIN | First person to make an orbital space flight (April 12, 1961): 2 wds. |
| KNOXJOHNSTON | Surname of the British sailor who was the first person to perform a single-handed, nonstop circumnavigation of the globe (4-8) |
| CHARLES | In about 1840, which naturalist was the first person to add wheeled legs to a chair, the precursor of the modern office chair? (7,6) |