| REACTIVE | Characterised by reaction |
| FAKE | Word that when followed by Reaction gives the title of a 2010s game show hosted by Matt Edmondson (4) |
| ESTER | Organic compound formed by reaction between an acid and an alcohol with elimination of water |
| LITHARGE | Inflamed with hot rage brought about by reaction to heavy metal (8) |
| HYDROLYZE | Word meaning to decompose a compound by reaction with water (9) |
| YELLOWFEVER | What is the sometimes fatal infectious disease transmitted by a mosquito and characterised by jaundi |
| DAGRAY | Disease characterised by anaemia that is caused by a lack of vitamin C (6) |
| ANOMIE | State or condition originally described by Emile Durkheim, characterised by hopelessness in society as a result of lack of structure or an absence of norms (6) |
| INDUSTRIAL | - Revolution; period of development characterised by the rise of steam power and mass production of goods that saw protests by the Luddites (10) |
| CATALEPSY | Medical condition characterised by a trance or seizure with a loss of sensation and consciousness accompanied by rigidity of the body |
| ALINE | Originally designed by Christian Dior in the 1950s, a style or silhouette of skirt characterised by a narrow waist widening to a full hem (1-4) |
| ROMANTIC | Art, music or literature characterised by an emphasis on feeling and content rather than order and form - like the kind of novels published by Mills and Boon? |
| MALARIA | An infectious disease characterised by recurring attacks of chills and fever, caused by the bite of an infected mosquito (7) |
| CHLOROSIS | Anaemia caused by iron deficiency characterised by greenish-yellow skin discoloration and usually seen in adolescent females |
| BOCAGE | Type of landscape in parts of rural France including Normandy characterised by pasture divided by hedgerows; or, woodland scenery represented in porcelain figurines (6) |
| BLIGHT | Any of various plant diseases characterised by withering or shrivelling without rotting, typically caused by fungi or bacteria (6) |
| RINGWORM | A skin disease characterised by circular patches produced by fungi (8) |
| SHRUBBY | Rush by ground around back of club characterised by woody plants (7) |
| EPILEPSY | Disease characterised by fits (8) |
| RAINY | Characterised by precipitation (5) |
