| OFASTART | Cause of a twitch during sleep, an excellent beginning (1,5,2,1,5) |
| ADREAM | Cause of a twitch during sleep, an excellent beginning (1,5,2,1,5) |
| SCIATICA | Ache with cold twitch during maladies, sporadically relapsing? (8) |
| CHICANE | Bends style - an excellent beginning (7) |
| FLYINGSTART | An excellent beginning (6,5) |
| ORTWO | "And sleep an act ___": Shak. |
| DOSS | Sleep - an easy task! (4) |
| SYMPTOMATIC | Sign of a twitch indicative of all parts of disorder |
| TIC | A bit of a twitch, somehow (3) |
| ECHO | Effect of a Twitch guest forgetting to mute their stream, perhaps |
| CLIP | Shareable segment of a Twitch stream |
| VOD | Recording of a Twitch stream, for short |
| AIR | Excellent beginning of reggae song |
| PLUMMET | Rush down, having encountered excellent beginning (7) |
| FIRSTCLASS | Excellent beginning to education (5,5) |
| PACER | Racehorse's power shown by excellent beginning to race (5) |
| DREAM | A series of mental images and emotions occurring during sleep (5) |
| APNOEA | What is a temporary cessation of breathing, especially during sleep? (6) |
| REM | A state of rapidly shifting eye movements during sleep (3) |
| SNORE | To breathe with a coarse rasping sound during sleep |
