| REINE | Catherine de Medici was one |
| HENRYII | Catherine de' Medici was his queen |
| EDEN | Some Catherine de Medici rebellious plot - the one we associate with gardeners, from the start (4) |
| ESSA | Pronoun for Catherine de' Medici |
| SPINACH | Catherine de' Medici is said to |
| YUILERIES | Jardin des -; gardens originally commissioned by Catherine de Medici (9) |
| DELORME | Philibert -; an architect who designed the first plans of the Tuileries Palace for Catherine de' Medici in the 16th century (2,1'4) |
| CHARLESIX | Catherine de' Medici and Henry II's son who ruled as king of France from 1560 until his death in 1574 (7,1,1) |
| ARTICHOKE | Globe -; edible thistle said to have been introduced to France by Catherine de Medici in the 16th century, depicted in designs by William Morris (9) |
| TUILERIES | Jardin des -; depicted in paintings by Manet and Pissarro, formal gardens next to the Louvre, originally commissioned by Catherine de Medici (9) |
| SERPENT | Drama starring Samantha Morton as Catherine de' Medici, The _ Queen (7) |
| MOTHERINLAW | Relation of Catherine de Medici to Mary, Queen of Scots (6-2-3) |
| MORTON | Catherine de' Medici in Starz series The Serpent Queen (8,6) |
| SAMANTHA | And 41 Down Catherine de' Medici in Starz series The Serpent Queen (8,6) |
| COSIMO | ___ de' Medici, first de facto Lord of Florence |
| UFFIZI | Art gallery whose building was originally commissioned by Cosimo I de' Medici to house the administrative offices of Florence (6) |
| LORENZO | Florentine ruler, - de' Medici, the Magnificent |
| PATRON | Lorenzo de' Medici, notably |
| PITTI | Palazzo -; palace in Florence bought by Cosimo I de' Medici in 1549, today divided into four museums (5) |
| CATHERINE | ___ de' Medici, influential 16th-century political figure and mother of three French kings (9) |
