| BANTINGANDBEST | Canadians who co-discovered insulin in 1921: 3 wds. |
| MACLEOD | John -; Scottish scientist who co-discovered insulin (7) |
| MEDICALADVANCEMENTS | 100th Anniversary! The discovery of Insulin in 1921 by Canadian researchers Banting and Best is among the greatest of these in the world: 2 wds. |
| BEST | Banting & ___ discovered insulin (4) |
| MAO | Chinese statesman who helped found the Chinese Communist Party in 1921 (3) |
| BAX | Arnold ?, English composer of symphonic poem Tintagel which premiered in 1921 (3) |
| ADAMS | Astronomer and mathematician who co-discovered Neptune; or, the athlete, who in 2012, became the first woman to win an Olympic boxing title (5) |
| JUNOBEACHCENTRE | WORLD WAR II - Museum in Courseulles-sur- Mer in France honouring the bravery and sacrifice of the Canadians who fought for our freedom in the Allied victory (More at #S-Down): 3 wds. |
| HEVESY | George de -; Nobel Prize-winning radio-chemist who co-discovered hafnium in 1923 (6) |
| IRA | Chemist Remsen who co-discovered saccharin |
| FRANCIS | Crick who co-discovered DNA structure |
| ABELSON | Philip --, American physicist who co-discovered the element neptunium (7) |
| FRANCISCRICK | Nobelist who co-discovered the structure of DNA |
| ALANHALE | Astronomer who co-discovered a comet with Thomas Bopp |
| PENZIAS | Physics Nobelist who co-discovered cosmic |
| IDA | Chemist Noddack who co-discovered rhenium |
| CURIE | Marie who co-discovered radium |
| LISE | Physicist Meitner who co-discovered nuclear ffssion |
| RAMSAY | Chemist who co-discovered "idle, without work" argon, "solar" helium, "hidden" krypton", "new" neon and "strange" xenon (6) |
| MEN | Canadians who were Without Hats (3) |