| PEYOTE | Cactus of Mexico and US (6) |
| TREECHOLLA | Shrub-like cactus of Mexico and south-west USA (4,6) |
| CANECHOLLA | Shrub-like cactus of Mexico and south-west USA (4,6) |
| RIOGRANDE | In Brazil, big money for energy divides parts of Mexico and America (3,6) |
| MOUSTACHE | Borders of Mexico and United States tense -- long legacy of Zapata? (9) |
| MESCAL | Spineless cactus of Mexico also called peyote (6) |
| SAMOA | Country in South America close to Mexico and America |
| CHOLLA | Spiny cactus of the genus Opuntia found in Mexico and the south-western US; from Spanish, 'head' or skull' (6) |
| DAHLIA | Any of several plants having tuberous roots and showy rayed variously coloured flower heads; native to the mountains of Mexico and Central America and Colombia (6) |
| JOSHUA | ___ tree, Yucca plant of Mexico and the south-west USA (6) |
| ELFOWL | Small bird of prey of Mexico and the southern USA (3,3) |
| CUBA | Largest and westernmost island of the West Indies, located at the intersection of the Atlantic Ocean, Gulf of Mexico and Caribbean Sea (4) |
| OCOTILLO | Flowering spiny shrub of Mexico and the south-western US (Fouquieria splendens) known by names including coachwhip, Jacob's staff and vine cactus (8) |
| GUAYULE | Bushy shrub in the aster family of Mexico and the southwestern US; a source of latex (7) |
| POPOCATEPETL | Volcano on the border of the states of Mexico and Puebla, central Mexico. The name in the Nahuatl means "Smoking Mountain." (12) |
| SAGUARO | Tree-sized cactus, Carnegiea gigantea, found in desert regions of Mexico and south-west US (7) |
| PESO | Currency unit of Mexico and other South and Central American countries |
| YUCATAN | ____ Peninsula, projection of Central America that includes parts of Mexico and Belize (7) |
| CONQUISTADOR | Spanish conqueror of Mexico and parts of South America in the 16th century (12) |
| MAYA | People of Mexico and central America |
