| LONGHORN | Breed of cattle formerly common in the southwestern U.S. (8) |
| MUSTANG | Small breed of horse found in the southwestern U.S. (7) |
| PUEBLO | Village in the southwestern U.S. (6) |
| HALON | Unreactive gaseous compound of carbon with bromine, iodine etc; formerly common in fire extinguishers but now known to deplete atmospheric ozone (5) |
| NEATEN | Tidy space used by cattle formerly (6) |
| MESA | Flat-topped hill with steep sides, common in the southwestern US (4) |
| SOMBRERO | A broad-brimmed hat, typically worn in Mexico and the southwestern U.S. (8) |
| COLORADO | Central southwestern U.S. state whose capital is Denver (8) |
| RANCHERO | Cattle farm worker in the southwestern US and Mexico (8) |
| APACHE | A member of a group of Native American peoples of the southwestern U.S.A. (6) |
| UTE | Eponymous people of the Southwestern U.S. |
| PEYOTE | Cactus of Mexico and the southwestern U.S. also called mescal (6) |
| BURSITIS | The inflammation of a small fluid-filled sac in the body, most common in the shoulders, hips, elbows or knees (8) |
| MOJAVE | Desert of the southwestern U.S. |
| GILA | ____ monster, a large, venomous, brightly coloured lizard native to Mexico and the Southwestern U.S. (4) |
| GILAMONSTER | A venomous lizard with strong jaws, native to the southwestern U.S. and Mexico (4,7) |
| BOUFFANT | Woman's puffed-out hairdo common in the 1960's |
| WILLIAMS | Surname of Welsh origin that is the third most common in the United Kingdom |
| DODDERER | What's less common in the German geriatric? (8) |
| HACIENDA | Large Spanish ranch, common in the Pampa Province of South America |
