| BIOMEDICINE | Bone broken by Lorenzo, say, requiring adoption of current stress-related science |
| TAMPA | Cheers with adoption of current measure in US city (5) |
| OBERMAN | Arm bone broken by Tracy-Ann as Auntie Val in Friday Night Dinner (7) |
| INCUS | The anvil bone broken by cousin, nothing less (5) |
| ROBOTICS | Source welcoming British science backing AI-related science? (8) |
| TENSION | Numbers working under current stress (7) |
| DONGIOVANNI | Opera by Mozart, with a libretto by Lorenzo Da Ponte, subtitled The Rake Punished |
| EMBRACEMENT | Adoption of cuddling me can be term used for it (11) |
| ELCID | Looking up bones broken by large Castilian hero (2,3) |
| CATHARSIS | Release and trim cast protecting bones broken by husband (9) |
| BRONZE | An alloy of copper and tin used by Lorenzo Ghiberti to make the doors of the Florence Baptistery and also by Andrea del Verrocchio and Donatello in notable equestrian sculptures (6) |
| COSIFANTUTTE | Italian language opera buffa by Wolfgang Amadeus Mozart whose libretto was written by Lorenzo Da Ponte |
| STREAKY | Trek, say, requiring clarification is marked with bands (7) |
| BARBERSHOP | Dance for Figaro, say, requiring a quartet? (6-4) |
| ORVIETO | Umbrian city whose cathedral has a west front designed by Lorenzo Maitani |
| FIBULA | Seen with this bone broken? That could be unfeasible (6) |
| NOSEJOB | Jo's bone broken in plastic surgery (4,3) |
| TROTT | England batsman quit 2013-14 Ashes tour with stress-related issues (5) |
| ACCENTUATE | Catherine can't go around EU - it's stress-related (10) |
| LINEN | Holland, say, requiring trade name |