| LAKEERIE | Body of water; southernmost of the Great Lakes of North America |
| SUPERIOR | Lake ---, the largest of the Great Lakes of North America (8) |
| ERIE | The southernmost of the Great Lakes of North America (4) |
| MICHIGAN | Lake ... is the only one of the five Great Lakes of North America that lies entirely within the Unit |
| MINDANAO | Southernmost of the major islands of the Philippines, and the second-largest after Luzon (8) |
| AVENTINE | Southernmost of the Seven Hills on which ancient Rome was built, in the district of Ripa (8) |
| HURON | Lake ---, the secondlargest of the Great Lakes of North America (5) |
| LAKESUPERIOR | The largest of the Great Lakes of North America (4,8) |
| ONTARIO | Smallest and most easterly of the Great Lakes of North America (7) |
| TRINIDAD | Southernmost of the Lesser Antilles |
| EIRE | Southernmost and fourth-largest of the five Great Lakes of North America (4) |
| LOCHNESS | Body of water in Scotland with more water than the collective lakes of England and Wales |
| STLAWRENCE | River system that includes the Great Lakes of North America (2,8) |
| CISCO | Any of various whitefish, of cold deep lakes of North America. (5) |
| GUAM | Largest and southernmost of the Mariana Islands in the W Pacific, and the westernmost territory of the United States (4) |
| ISLAY | Southernmost of the Inner Hebrides, known as 'The Queen of the Hebrides' (5) |
| ROTA | Southernmost of the Northern Marianas in the western Pacific, known as the 'Friendly Island' (4) |
| JERSEY | Southernmost of the Channel Islands, and the second-closest to France after Alderney (6) |
| TAMILNADU | Southernmost of the 28 states of India, formerly (until 1968) known as Madras (5,4) |
| SKYROS | Greek island, the southernmost of the Sporades (6) |
