| BOOKMAKERS | Betting agents such as the UK's Ladbrokes or William Hill |
| SUBJECTS | Word for thinking agents, such as topics or studies; or, citizens (8) |
| BOOKMAKER | Betting agent (9) |
| MOORE | Brian ..... , winner of the 2010 William Hill Sports Book of the Year award (5) |
| TELL | Order William Hill to give away secrets (4) |
| CHAGRIN | Irritation shown by gambler cleaned out in William Hill, say (7) |
| STAYSON | Head of Ladbrokes, described in lesson, somehow does the job of a retailer (5,2) |
| CLAYTON | Jonny ....... , 2021 Ladbrokes Masters darts tournament winner (7) |
| BETS | Goes to Ladbrokes? (4) |
| PATHOGEN | Agent such as a virus or bacterium that can cause disease (8) |
| DYE | Colouring agent such as for fabric or hair (3) |
| INDIANINK | Artist's mixture of lampblack, water, and a binding agent such as shellac |
| GREENHOUSEGAS | Chemical agent such as carbon dioxide leads to flatulence in hothouse (10,3) |
| LEAVENED | Fermented and risen by adding an agent such as yeast (8) |
| STIMULANT | Agent such as caffeine causing temporary alertness (9) |
| SPY | Agent such as Austin Powers |
| COOKIES | For example, William Hill's losing billions following cold food (7) |
| GOWER | Peninsula in Wales including the Mumbles and Rhossili Bay that was designated as the UK's first Area of Outstanding Natural Beauty in 1956 (5) |
| LIZ | Name the Foreign Secretary who has replaced David Frost as the UK's chief Brexit negotiator. (3,5) |
| TRUSS | Name the Foreign Secretary who has replaced David Frost as the UK's chief Brexit negotiator. (3,5) |