| BENIGNI | Besides Olivier, he's the only person to direct himself to a Best Actor Oscar |
| OLIVIER | Until Roberto Benigni did it in 1998, he was the only person to direct himself to a Best Actor Oscar |
| ADAM | "Ma...da? come back!" cried he, the only one never to have had either? (4) |
| IDI | Amin played to a Best Actor Oscar by Forest Whitaker |
| MALCOLM | Denzel played him to a Best Actor nomination in 1993 |
| HAM | Hard person to direct |
| THORN | The only person to play in the winning team of an NRL grand final, a State of Origin rugby league series and a Rugby World Cup final (5) |
| RUTHPRAWERJHABVALA | The only person to have won both a Booker Prize and an Oscar (4,6,8) |
| IVANISEVIC | Goran ___, the only person to win the men's singles title at Wimbledon as a wildcard |
| ERICCLAPTON | British guitarist, the only person to be inducted to the Rock & Roll Hall of Fame three times |
| GEORGEDEWEY | The only person to have been appointed Admiral of the Navy in the US (6,5) |
| PAULING | The only person to have won the Nobel Prize for Chemistry and for Peace, and known for his research in quantum chemistry and molecular biology (last name only) |
| SANGER | Frederick -; considered the "father of genomics", the only person to have won two Nobel Prizes in chemistry (6) |
| RODLAVER | The only person to have won tennis's Grand Slam as an amateur and a professional (3,5) |
| TAFT | William Howard ____ is the only person to be both president and chief justice of the USA |
| CURIE | Surname of the woman who is the only person to win two Nobel Prizes in different fields (5) |
| NINA | Garcia who is the only person to be a judge on every season of Project Runway |
| FREDWINTER | The only person to have won the Cheltenham Gold Cup, Champion Hurdle and Grand National as both jockey and trainer |
| HEPBURN | Who is the only person to have won four Academy Awards for acting? (7) |
| LINUSCARLPAULING | US chemist who became the only person to have won two unshared Nobel Prizes (5,4,7) |
