| WALLOP | Beer, big hit (6) |
| OEDIPAL | Reference work on beer, large and so complex? |
| PRIMAL | and 4ac, Therapeutic release from Prince: one big hit, backed by "60s group (6,6) |
| SLEDGE | This became a big hit with its handlers (6,6) |
| HAMMER | This became a big hit with its handlers (6,6) |
| RECORD | Big hit for less sensitive individual strike history (6,3,3,6) |
| ONEHIT | Big hit for less sensitive individual strike history (6,3,3,6) |
| NUMBER | Big hit for less sensitive individual strike history (6,3,3,6) |
| SCREAM | see 1ac, Therapeutic release from Prince: one big hit, backed by "60s group (6,6) |
| WASABI | Hot root found was a big hit (6) |
| BUFFET | Help-yourself food, big hit (6) |
| JOANNA | A big hit for Scott Walker in 1968 (6) |
| FAMOUS | When Will I Be ___?, first big hit for Bros (6) |
| SLOGAN | Catchphrase is a big hit primarily before end of election (6) |
| PINATA | A big hit for Mexican and US children at Christmas (6) |
| SPLASH | Bob and Penny get a whip - it is a big hit (6) |
| LITTLE | Ed Sheeran song: big hit for any wee lassie. (6,4) |
| KARPOV | Big hit includes funny rap verse, getting Russian ace on board (6) |
| STOKER | Staffordshire team needing runs: his big hit was 6 |
| GAMBIT | Chess-based drama The Queen's ___ was a big hit for Netflix in 2020. (6) |
