| AMYSHERALD | Artist who painted Michelle Obama's portrait for the Smithsonian's National Portrait Gallery: 2 wds. |
| KEHINDEWILEY | Artist who painted Barack Obama's portrait for the National Portrait Gallery: 2 wds. |
| TUBMAN | Proposed portrait for the $20 bill |
| OPART | Geometric genre in a gallery: 2 wds. |
| SIMMIEKNOX | Artist who painted Bill and Hilary Clinton's portraits for the White House collection: 2 wds. |
| INDEPENDENCEAVE | D.C. thoroughfare with the Smithsonian's National Air and Space Museum |
| MOONROCKS | Some are displayed in the Smithsonian's National Air and Space Museum |
| ELMO | Red Muppet in the Smithsonian's National Museum of American History |
| STRONG | Former director of the V&A and also the National Portrait Gallery, author of books including The Artist and the Garden, A Country Life and The Elizabethan Image (6) |
| KENNETHFRANKCOLES | 1979 William Dargie portrait, now part of the National Portrait Gallery collection? (7,5,5) |
| OBAMA | Subject of a Kehinde Wiley portrait in the National Portrait Gallery |
| CHANDOS | Most famous of the portraits that may depict Shakespeare, located at the National Portrait Gallery, London (7) |
| ANNIGONI | Artist whose 1969 painting of Queen Elizabeth II is in the National Portrait Gallery (8) |
| EDITHCAVELL | Opposite the National Portrait Gallery in London is a statue commemorating this WWI nurse and humani |
| SAMSMITH | Singer/songwriter depicted in Gloria at the National Portrait Gallery (3,5) |
| ARTMUSEUM | National Portrait Gallery, e.g. |
| MISSYELLIOTT | "Work It" rapper who was in the back seat during Michelle Obama's "Carpool Karaoke" segment: 2 wds. |
| ARTOO | Robot included in the Smithsonian's "101 Objects That Made America," briefly |
| OILPAINT | Artist's medium, or impressively large, portrait for starters isn't common (3,5) |
| DANIELRADCLIFFE | As a 16-year-old actor, youngest nonroyal with an individual portrait in Britain's National Portrait |