| MERINO | Antimicrobial wool obtained from Spanish sheep (6) |
| MANUKA | Type of honey native to New Zealand that has antimicrobial properties (6) |
| SORBIC | Antimicrobial kind of acid |
| SULPHA | Drugs that were antimicrobial agents |
| CASHMERE | A fine, soft wool obtained from a type of goat (8) |
| CAROLE | Vehicle getting shout of approval from Spanish girl (6) |
| BARSAC | Apart from Spanish white wine, mostly French white wine (6) |
| DEPART | Escape from Spanish ambush coming back (6) |
| VIGOUR | Robust force from Spanish and Babylonian cities (6) |
| ARAGON | A student event being aired from Spanish region (6) |
| SIERRA | From Spanish, what is a long jagged mountain chain? (6) |
| ESCAPE | Flee from Spanish promontory (6) |
| ESTEEM | High respect from Spanish side, I hear (6) |
| CHOLLA | Spiny cactus of the genus Opuntia found in Mexico and the south-western US; from Spanish, 'head' or skull' (6) |
| FLAUTA | A rolled taco/tortilla, aka a taquito, whose name, from Spanish for "flute", refers to its flageolet-like shape (6) |
| CAJOLE | Persuade knave to return, mostly getting encouragement from Spanish? |
| ARMADA | Fleet of warships, from Spanish |
| MALAGA | Parent brings a local girl back from Spanish place |
| ELPASO | Border city in Texas whose name translated from Spanish means 'the crossing place' (2,4) |
| ELFLOCKS | The Spanish sheep have tangled hair (8) |