| ACINONYX | Animal genus in the cat family (Felidae) whose sole extant member is the cheetah (8) |
| LEIPOA | Australian bird genus of the family Megapodiidae whose sole extant member is the malleefowl (6) |
| TIGER | Largest member of the cat family (Felidae). It is endangered throughout its range, which stretches from the Russian Far East through parts of North Korea, China, India, and Southeast Asia to Sumatra. |
| LAUGHINGHYENA | Familiar name for the sole extant member of the genus Crocuta |
| VARANUS | Type and sole extant genus of the Varanidae. |
| TUATARA | Only extant member of the order Rhynchocephalia of large spiny lizardlike diapsid reptiles of coastal islands off New Zealand. |
| ERYNGIUM | Plant genus in the parsley family (Apiaceae) whose members include the European sea holly (8) |
| TROLLIUS | Plant genus in the family Ranunculaceae to which the globeflowers belong (8) |
| TRAGOPAN | Bird genus in the family Phasianidae commonly known as the horned pheasants (8) |
| AGNATHAN | Primitive vertebrate whose extant members are the lampreys and hagfishes; from Greek, 'without jaw' (8) |
| MIQUELIA | Genus in the flowering plant family Icacinaceae (8) |
| CAMASSIA | Genus in the asparagus family commonly called quamash (8) |
| MENANDER | Comic dramatist of ancient Greece whose sole complete extant work is Dyskolos (8) |
| RATRHYME | More than one's in The Cat Sat on The Mat (Cameron's doggerel) (3-5) |
| PRUNELLA | This genus in the mint family includes selfheal |
| EMPLOYEE | Staff member is the first person to go over strategy with pair of middlemen |
| BARBADOS | Island whose sole Olympic medal to date won by sprinter Obadele Thompson at Sydney 2000 (8) |
| SEEDIEST | Like the cheetah, among land animals |
| KIRKLAND | Chris ___, goalkeeper whose sole England cap in 2006 earned his father and friends A£10,000 each for a bet made eleven years earlier |
| CERATONIA | Small genus of flowering trees in the pea family whose best known member is the carob tree |
