| TRACHOMA | An eye infection affecting over 40 million people worldwide |
| INFLUENZA | The epidemic of the contagious disease at the end of WWI is estimated to have killed 40 million people |
| HBV | An estimated 257 million people worldwide are chronically infected with this liver disease (3) |
| KOREAN | Language spoken by approximately 60 million people worldwide (6) |
| RUMOURS | 1977 album that has sold over 40 million copies worldwide |
| GOTOTHERAPY | What over 40 million U.S. adults do annually |
| KANGAROOS | Australia has over 40 million of them |
| STYE | An eye infection that's also known as a hordeolum (4) |
| PAWAN | Actor-politician who underwent urgent surgery for an eye infection. (First name) (5) |
| TEA | Name, ultimately derived from the Chinese character e representing "plant, people, tree, wood", of the camellia-derived hot beverage or brew "cha", enjoyed by billions of people worldwide (3) |
| EOCENE | From 58 million to 40 million years ago |
| WHATSAPP | Messaging service used by more than two billion people worldwide |
| ATHLETESFOOT | A fungal infection affecting mainly the skin between the toes (8,4) |
| HANUKKAH | Eight-day festival during which Jewish people worldwide light menorahs |
| TUBERCULOSIS | Communicable disease caused by infection, affecting the lungs (12) |
| FISHPOX | Viral infection affecting carp mostly (*fix shop) (4,3) |
| DUTCHELMDISEASE | Fungal infection affecting trees first isolated in the Netherlands in 1921 (5,3,7) |
| STAFFSTAPH | Infection affecting a workforce? |
| FREDHOLLOWS | New Zealand/Australian ophthalmologist who restored the sight of thousands of people worldwide (4,7) |
| DALLAS | 40 million plus watched it one 1980 night |